Protein name:
Interleukin enhancer-binding factor 2 ;
Alternative:
Nuclear factor of activated T-cells 45 kDa ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Forms heterodimers with ILF3. ILF2-ILF3 heterodimers may also bind to PRKDC/XRCC7: this may stabilize the interaction of PRKDC/XRCC7 and the heterodimeric complex of G22P1/KU70 and XRCC5/KU80. Forms a complex with ILF3, YLPM1, KHDRBS1, RBMX, NCOA5 and PPP1CA. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with IGF2BP1.
Function:
Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA.
Subcellular Location:
Nucleus
nucleolus
Cytoplasm
Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein Attributes:
50:
MRGDRGRGRG | GRFGSRGGPG | GGFRPFVPHI | PFDFYLCEMA | FPRVKPAPDE |
100:
TSFSEALLKR | NQDLAPNSAE | QASILSLVTK | INNVIDNLIV | APGTFEVQIE |
150:
EVRQVGSYKK | GTMTTGHNVA | DLVVILKILP | TLEAVAALGN | KVVESLRAQD |
200:
PSEVLTMLTN | ETGFEISSSD | ATVKILITTV | PPNLRKLDPE | LHLDIKVLQS |
250:
ALAAIRHARW | FEENASQSTV | KVLIRLLKDL | RIRFPGFEPL | TPWILDLLGH |
300:
YAVMNNPTRQ | PLALNVAYRR | CLQILAAGLF | LPGSVGITDP | CESGNFRVHT |
350:
VMTLEQQDMV | CYTAQTLVRI | LSHGGFRKIL | GQEGDASYLA | SEISTWDGVI |
390:
VTPSEKAYEK | PPEKKEGEEE | EENTEEPPQG | EEEESMETQE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Mouse Interleukin enhancer-binding factor 2
ELISA Kit for Mouse Interleukin enhancer-binding factor 2
ELISA Kit for Mouse Interleukin enhancer-binding factor 2
CLIA Kit for Mouse Interleukin enhancer-binding factor 2
CLIA Kit for Mouse Interleukin enhancer-binding factor 2
CLIA Kit for Mouse Interleukin enhancer-binding factor 2
Polyclonal Antibody for Mouse Interleukin enhancer-binding factor 2
Polyclonal Antibody for Mouse Interleukin enhancer-binding factor 2
Polyclonal Antibody for Mouse Interleukin enhancer-binding factor 2
Monoclonal Antibody for Mouse Interleukin enhancer-binding factor 2
Monoclonal Antibody for Mouse Interleukin enhancer-binding factor 2
Monoclonal Antibody for Mouse Interleukin enhancer-binding factor 2
Protein for Mouse Interleukin enhancer-binding factor 2
Protein for Mouse Interleukin enhancer-binding factor 2
Protein for Mouse Interleukin enhancer-binding factor 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.
"The transcriptional landscape of the mammalian genome."
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[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
strain :
NOD .
tissue :
Head .
tissue :
Medulla oblongata .
tissue :
Spleen .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Czech II .
tissue :
Mammary tumor .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH ILF3
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE;TISSUE SPECIFICITY